To run a business

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to run (a business, a company): to operate, to direct, to oversee, to manage (a business, a company)
My cousin runs a small surf shop in Santa Cruz. He started there as an employee and now, 20 years later, he owns the place.
to run (a test): to do, to carry out, to execute (a test)
The doctor has to run a few tests before I can leave the hospital. He needs to see if I'm diabetic.

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